Which specific chromosomal aberration involves the detachment, 180-degree rotation, and reinsertion of a segment of a chromosome within the same chromosome?

💡 Solution & Explanation

Inversion is a structural chromosomal mutation in which a chromosome breaks in two places, the internal segment flips upside down by 180 degrees, and reinserts into the chromosome, altering the linear gene sequence without changing the total amount of genetic material. Deletion removes chromosomal segments, duplication repeats them, and translocation transfers segments between non-homologous chromosomes. Inversions can be pericentric if they include the centromere or paracentric if restricted to one arm.