General Science • BiologyEasy
Which enzyme catalyzes the unwinding of the DNA double helix by breaking hydrogen bonds between base pairs during DNA replication?
A. DNA polymerase
B. DNA helicase✓ Correct Answer
C. RNA primase
D. DNA ligase
💡 Solution & Explanation
DNA helicase is the specialized enzyme responsible for breaking the hydrogen bonds holding the complementary nitrogenous bases together, thereby unwinding the double helix during DNA replication. Alternative enzymes like DNA polymerase synthesize the new strands by adding nucleotides, whereas DNA ligase seals the nicked sugar-phosphate backbone of Okazaki fragments.
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