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General Science • BiologyMedium

During the process of aerobic cellular respiration in eukaryotic cells, where does the Krebs cycle take place?

A. Cytoplasm of the cell
B. Matrix of the mitochondria✓ Correct Answer
C. Inner mitochondrial membrane
D. Stroma of the chloroplast

💡 Solution & Explanation

The Krebs cycle or citric acid cycle occurs within the mitochondrial matrix, where acetyl-CoA is oxidized to carbon dioxide, generating NADH and FADH2 electron carriers. Glycolysis takes place in the cytoplasm, oxidative phosphorylation occurs across the inner mitochondrial membrane, and the Calvin cycle occurs in chloroplast stroma. Mitochondria are often termed the powerhouse of the cell.

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