General Science • BiologyMedium
Which enzyme is responsible for the unzipping of the DNA double helix during DNA replication?
A. DNA Polymerase
B. DNA Helicase✓ Correct Answer
C. DNA Ligase
D. RNA Primase
💡 Solution & Explanation
During DNA replication, DNA helicase utilizes energy derived from ATP hydrolysis to break the hydrogen bonds holding the two complementary strands together, successfully unzipping the double helix. Alternative enzymes such as DNA polymerase handle chain elongation, whereas DNA ligase seals single-strand nicks in the sugar-phosphate backbone. RNA primers are synthesized by primase to initiate the action of DNA polymerase.
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