General Science • BiologyMedium
Which enzyme is responsible for synthesizing RNA primers required during DNA replication?
A. DNA polymerase
B. RNA primase✓ Correct Answer
C. DNA ligase
D. Helicase
💡 Solution & Explanation
RNA primase is a specialized RNA polymerase that synthesizes short RNA primers, providing the essential free 3'-OH group required by DNA polymerase to initiate strand elongation during replication. DNA polymerase cannot start a new chain from scratch, and DNA ligase functions later to seal nicked phosphodiester backbones. Molecular biology concepts regarding enzyme functions during replication are frequently featured in competitive biology syllabi.
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