Which immunoglobulin antibody is primarily involved in mediating immediate hypersensitivity reactions and allergic responses in humans?

💡 Solution & Explanation

Immunoglobulin E binds to mast cells and basophils, triggering degranulation and the release of inflammatory mediators like histamine during immediate allergic reactions. Other classes like IgG and IgM are primarily involved in secondary and primary immune responses against bacterial and viral pathogens respectively.