General Science • BiologyHard
Which hormone secreted by the duodenal mucosa stimulates the pancreas to secrete a watery fluid rich in bicarbonate ions to neutralize gastric acid?
A. Cholecystokinin
B. Secretin✓ Correct Answer
C. Gastrin
D. Somatostatin
💡 Solution & Explanation
Secretin is a peptide hormone released by S cells in the proximal small intestine in response to acidic chyme entering from the stomach, prompting pancreatic duct cells to release bicarbonate-rich fluid. Cholecystokinin primarily stimulates gallbladder contraction and pancreatic enzyme secretion rather than bicarbonate production. Gastrin stimulates hydrochloric acid secretion by parietal cells in the gastric mucosa. Somatostatin acts as a universal inhibitory peptide suppressing gastrointestinal hormone release.
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